There is a gradual increase in the number of college students infected with HIV. Currently, according to statistics, the main cause of HIV infection among college students is homosexuality, especially among gay men. Gay men mainly because of the different ways of sexual intercourse, mainly anal sex, which can easily lead to the breakage of local skin and mucous membrane. Some of the gay men may be sexually promiscuous, which is the reason for the increase in the rate of HIV infection. For these patients, timely treatment is needed, and the process of treatment requires attention to monitoring the number of HIV. If the number of HIV is decreasing, the treatment is effective and the infection is decreasing. Gay men need to be clean, have regular sexual partners, and wear condoms during sex.