Acute itchy rash usually heals spontaneously in 2-3 weeks, while chronic itchy rash is treated, usually in about 6 months to 1 year. Acute itchy rash is usually self-healing and may recur after self-healing. Treatment is mainly symptomatic treatment, anti-inflammatory and anti-itching, prevention of secondary infection, etc. Chronic itchy rash has a more complex etiology and it is difficult to find the exact cause clinically, so the treatment time is relatively long. The treatment is to try to find the cause of the disease and try to cure it. The principle of treatment is mainly local anti-inflammatory and anti-itch; if the systemic symptoms are obvious, oral medication is needed, such as short-term application of a small amount of hormonal drugs, immunosuppressants; physical therapy such as bran bath, starch bath, and narrow medium-wave ultraviolet radiation can also be carried out, and the efficacy is also very good. Itchy rash is easy to diagnose and difficult to treat, and is prone to recurrence after cure. In addition to medication, preventive treatment should be given for the possible causes of itchy rash to prevent the production and recurrence of itchy rash, such as preventing insect bites, regulating gastrointestinal function, improving nutrition and hygiene, and early intervention for patients with mental illness.