The patient is an Italian, female, 62 years old, who has suffered from right chronic secretory otitis media for more than 10 years, with long-term right ear congestion, hearing loss, head swelling and discomfort, which seriously affects work and life. Since the onset of the disease, she had received medication and eustachian tube blowing, but the treatment was not effective. She had undergone tympanic tube placement six times, but all of them relapsed due to the thick middle ear fluid blocking the ventilation tube or the ventilation tube falling off. This time, the patient came to our otology department with a fluke mentality. The use of tympanic membrane placement is symptomatic (passive) treatment and should not be used because of repeated treatment failures, while eustachian tube recanalization is active (causal) treatment and can be attempted using the minimally invasive surgery —- pharyngo-drum balloon dilatation, which is currently advanced in the world. After admission, the patient was diagnosed with chronic secretory otitis media on the basis of a “B” tympanic chamber pressure map in the right ear, conductive deafness in the right ear on electrical audiometry, and middle ear mastoid CT: blurred air spaces in the right mastoid cavity and signs of fluid accumulation in the middle ear cavity. The patient was diagnosed with chronic secretory otitis media and underwent balloon dilatation of the eustachian tube on January 14, 2015, and jelly-like secretions were seen flowing from the pharyngeal opening of the eustachian tube when the balloon was withdrawn. The main cause of secretory otitis media (also called “glue ear”) is the dysfunction (obstruction) of the eustachian tube, and the anatomical characteristics of the eustachian tube make clinical treatment very difficult. A series of complications can occur. Eustachian tube balloon dilation is performed by introducing a balloon into the eustachian tube through the pharyngeal opening of the eustachian tube under the guidance of a nasal endoscope, and then expanding the balloon with a pressure pump after crossing the eustachian tube stenosis to achieve the effect of eustachian tube recanalization. It is a new international minimally invasive surgical treatment method with short operation time and good efficacy.