Nausea, regurgitation and vomiting in diabetic patients may be caused by poor glycemic control, adverse reaction to glucose-lowering medications, and comorbid gastrointestinal disorders, which can be treated by non-pharmacologic and pharmacologic means. If the adverse reaction of hypoglycemic drugs, gastrointestinal adverse reaction is serious, you can follow the doctor’s advice to change the drug. 1. Poor glycemic control: Patients with poor glycemic control and diabetic complications, such as diabetic ketoacidosis, may experience nausea, vomiting and other symptoms. Blood glucose should be controlled immediately, follow the doctor’s instructions to regulate the injection of insulin therapy, while with low-salt, low-sugar, low-fat diet, regular aerobic exercise, can effectively reduce blood glucose. 2. Adverse reactions to hypoglycemic drugs: such as metformin, acarbose and other hypoglycemic drugs, common adverse drug reactions include nausea, vomiting, diarrhea and other symptoms. It is recommended to give small doses of drugs to reduce gastrointestinal symptoms, and if the reaction is serious, the drug can be discontinued and replaced by other hypoglycemic drug treatment as prescribed by the doctor. 3. Combined gastrointestinal diseases: such as chronic gastritis, peptic ulcer and other gastrointestinal diseases, nausea, range, vomiting, abdominal distension and other symptoms, you need to go to the hospital in time, after clarifying the cause of the disease, and then give medication as prescribed by the doctor, such as omeprazole, bismuth potassium citrate and so on. Diabetic patients with uncomfortable symptoms, it is recommended to promptly seek medical attention.