The TNM stage and risk of recurrence stratification of differentiated thyroid cancer were evaluated based on available clinical data to determine the extent of thyroid and cervical lymph nodes that should be removed by surgery. Then, based on the risk of reoperation, convenience of follow-up, patient’s willingness and compliance, and other factors, we will decide the follow-up plan based on adequate communication with the patient: ① If reoperation is needed, it is recommended to perform it as early as the patient’s condition allows or after the edema in the operated area has subsided (after 3 months). In view of the increased risk of serious surgical complications associated with reoperation compared with the first operation, special attention should be paid to the protection of the parathyroid glands and the recurrent laryngeal nerve during reoperation. (ii) Patients with a low risk of recurrence may be followed up if the affected lobe was removed during the first surgery. (3) For patients with low risk of recurrence, if the first surgery is a partial lobectomy (only a small amount of non-tumor glandular tissue is preserved), if the follow-up is convenient and the patient’s compliance is good, the surgery can be suspended and the patient can be closely followed up with TSH suppression therapy and then surgically treated again if abnormalities are detected.