Small cell lung cancer bone metastasis will show elevated plasma alkaline phosphatase and elevated blood calcium. At the same time, patients will also have abnormal examination results in imaging examination. When bone metastasis occurs in patients with small cell lung cancer, bone quality will be destroyed, and patients will have elevated serum alkaline phosphatase when they undergo blood biochemical examination. In addition, when small cell lung cancer metastasizes to bones, the bones may be destroyed, and if the patient develops extensive osteolytic lesions, the blood calcium examination will show elevated blood calcium. X-ray examination of small cell lung cancer patients with bone metastasis will find that the local lesions are irregular, with unclear boundaries, and the localized lesions will be sieve-like or worm-eaten. It is recommended that patients with small-cell lung cancer need to consult doctors in time when bone metastasis is suspected, and doctors will judge the condition according to the examination results and patients’ physical condition, and give corresponding treatment measures. In addition, patients should undergo chemotherapy, radiotherapy and surgery for small cell lung cancer. Patients should ensure enough rest and take care of balanced nutrition in diet.