The use of progesterone during pregnancy does not lead to increased pregnancy sickness. Progesterone is a progesterone drug that is mainly used to treat conditions such as pre-eclampsia and habitual miscarriage caused by insufficient luteal function. In case of low progesterone during pregnancy or fertility assistance, progesterone can be used in moderation for fetal preservation treatment. In contrast, most women experience pregnancy vomiting in early pregnancy, mainly related to human chorionic gonadotropin and estrogen. As the secretion of human chorionic gonadotropin increases and the level of estrogen rises, the degree of pregnancy vomiting will also increase. Therefore, progesterone does not affect the early pregnancy response and cause an increase in pregnancy sickness. If the blood HCG in pregnant women increases significantly, it often leads to slight edema of the mucous membrane of the gastrointestinal tract and disorders of the gastrointestinal function, which may be manifested as prolonged gastric emptying time and reduced gastric acid secretion, which may lead to severe vomiting and even dehydration or electrolyte disorders. If vomiting is obvious during pregnancy, you should pay attention to avoid contact with smells or foods that can easily induce vomiting, and eat a light and easily digestible diet, such as milk, lotus root powder, thin porridge and fresh fruits and vegetables, and avoid eating spicy, stimulating and greasy foods. Eat less and more meals, and try not to have an empty stomach in the morning. Try to relax, pay attention to rest, ensure sufficient sleep, avoid exertion and mental tension, can be under the guidance of the doctor for drug antiemetic treatment.