Frequent tooth pain may be caused by dental caries or chronic periapical infection, chronic periodontitis, etc. Patients are recommended to seek medical treatment. According to the degree of patient’s condition and personal situation, treatment plan can be made, and painkillers such as ibuprofen and acetaminophen can be taken appropriately to relieve the symptoms, or antibiotics can be used for anti-inflammation, etc. The common treatment includes: 1.tooth decay: surgical removal of carious tissue and selection of suitable repair material for restoration. If the degree of caries is deeper, root canal treatment is also needed; 2, chronic periapical infection: antibiotics can be used to prevent and control the infection, cefradine, cefixime, metronidazole, etc. are commonly used clinically. Some of the inflammation is more serious, or accompanied by dental nerve damage, root canal treatment is required. If there is an abscess in the root of the tooth, it also needs to be incised and drained to drain the pus. The symptoms can be effectively improved; 3. Chronic periodontitis: plaque and tartar can be completely removed by scaling to reduce the stimulation of the gums. Review 6-8 weeks after basic treatment, if there are still periodontal pockets, tartar and other conditions feasible periodontal flap surgery. In the case of loose teeth, ligature fixation is required to adjust the occlusal relationship, and if the teeth are severely loose and cannot be improved, they can be extracted if necessary. In addition, toothache caused by underlying diseases such as diabetes and anemia should be actively controlled and treated for underlying diseases, which is conducive to improving the symptoms of toothache; 4. Pulpitis: clinical symptoms are mostly improved through pulp capping, pulpotomy and root canal treatment, which can effectively treat toothache.