Common diseases that manifest as blisters on the skin include the following. 1. Viral infections: 1. Herpes simplex: It occurs around the mouth and nose, or on the vulva and buttocks. Easily recurring. The manifestation is a bunch of small bubbles, accompanied by itching or pain, easy to break. It is easy to recur when there is a fire or resistance. It usually gets better on its own in a week. 2, shingles: commonly known as tangled dragon. It is a common disease that occurs in the winter and spring, mostly in the elderly. They are unilateral and rarely appear as bilateral lesions. The manifestation is a cluster of blisters or papules, mostly accompanied by local pain. 3, chickenpox: winter and spring seasons occur in adolescents. They appear as small blisters, mostly green bean-sized, surrounded by a red halo and accompanied by definite itching, starting from the face and trunk. The first day of illness may be accompanied by fever. The blisters quickly break on their own. It is clearly contagious and requires all lesions to be crusted over before it becomes non-contagious. Allergy-related: 1. Eczema: It is a common disease. Erythema, blisters, papules and other manifestations, accompanied by significant itching. Acute attacks of skin lesions will appear blisters, oozing. The blisters of eczema are generally small. Rarely, they are larger than the size of a green pea. But there can be multiple blisters. 2, contact dermatitis: inappropriate topical medication, local erythema, itching, serious will appear blisters. For example, some patients have localized erythema blisters in the same shape as the cream after applying the cream. Or after topical application of safflower oil, Jingwanhong and other bruises, erythema and blisters appear. 3, severe drug rash (severe drug allergy): manifested by taking certain drugs (such as antibiotics, antipyretics, Chinese medicine, etc.) after the appearance of erythema, blisters, or pustules throughout the body. Oral and vulvar ulcers. It can be accompanied by a variety of systemic manifestations such as fever and elevated liver function. Autoimmune herpetic dermatoses (pemphigus, pemphigoid, herpes-like dermatitis, etc.) occur in middle-aged and elderly people. The course of the disease is mostly chronic, with early eczema-like changes and scattered erythema, papules and blisters all over the body. It may be accompanied by pruritus. If eczema is treated and does not improve in the long term, it is recommended that pathology and immunofluorescence tests be performed at a hospital to confirm the diagnosis. There are many other diseases that can manifest as blisters on the skin. Here is a brief description of only the most common ones. For the reference of all sufferers.