Medications for sciatic nerve pain are divided into three main categories: first, painkillers: such as Loftanzine extended-release tablets or Meloxicam tablets. Second, blood circulation and blood stasis drugs: such as blood circulation and pain relief capsules, salvia tablets, etc. Third, nerve-nourishing drugs: such as methylcobalamin and other drugs. Sciatic nerve pain may be caused by a herniated lumbar disc compressing the nerve root, or it may be caused by peripheral nerve entrapment, such as pear-shaped muscle syndrome, or peripheral neuropathy, which requires a timely visit to the hospital for an interview with a doctor, who will make a preliminary analysis with physical examination. If the sciatic nerve is compressed by the protruding disc, you need to consider traction, bed rest, with acupuncture and physiotherapy, serious compression needs to consider surgery.