”The success rate of IVF is generally about 40%. What factors can affect the success rate of IVF is a concern for patients who are ready to undergo IVF treatment. The doctors of the Reproductive Center of the Fourth Hospital of Hebei Medical University will explain the factors that affect the success rate of IVF: 1. The patient’s own conditions: age over 35 years old, the ovarian reserve function decreases, the quality of oocytes changes, the chance of chromosomal abnormalities increases, the embryo implantation rate decreases and the success rate is low; the endometrium is also an important condition that affects the pregnancy rate, a good endometrium provides good conditions for embryo implantation, a bad endometrium is like a poor A good endometrium provides good conditions for embryo implantation, while a bad endometrium is like barren land where good seeds can hardly grow. Mechanical damage to the endometrium, uterine fibroids and adenomyosis can affect it to different degrees; smoking, high body mass index and mental factors can also affect the success rate of IVF. 2.Controlled superovulation protocol: Individualized controlled superovulation protocol is important. The timing of drug initiation, the number of days of medication and the patient’s ovarian response are important, and only by providing good eggs for the embryo culture room can high quality embryos be cultured. 3.Technical level of embryo culture: The embryo culture room adopts laminar flow purification, which greatly improves the air quality in the laboratory; all kinds of culture fluid, plastic utensils and other consumables used in embryo culture are strictly tested before use to make sure they are non-toxic and harmless to the growth of embryos. The laboratory personnel are also very skilled in handling the whole embryo, gently and quickly, without causing artificial damage to the embryo. 4. The process of embryo transfer: the appropriate transfer tube is selected and placed precisely in the right place in the uterine cavity under the guidance of ultrasound, and the whole transfer process is light, accurate and stable to avoid damaging the endometrium.