The left eyelid jumping is mostly seen in facial muscle spasm and focal seizures. Facial muscle spasm is mainly caused by vascular compression and stimulation in the facial nerve travel, which can be manifested as involuntary eyelid jumping in mild cases and involuntary twitching of one side of the facial muscles in severe cases, which seriously affects the patient’s image and temperament. The disease is a neurological disease, the common clinical treatment drugs are carbamazepine, diazepam, vitamin B12, etc. In addition, local injection of botulinum toxin can also receive good results. If the above treatment is not effective, microvascular decompression can be performed to relieve the facial nerve compression with better clinical results. Focal seizures can also be manifested as eyelid fluttering, and seizure waves can be detected by EEG examination.