Clinically, to ensure the accuracy of nucleic acid test results, it is generally recommended that alcohol not be consumed for at least half an hour or one hour prior to the nucleic acid test. However, there is a lack of clinical studies on whether or not the accuracy of nucleic acid test results is affected by drinking alcohol, and there is no valid research data to prove whether or not it is affected. If time permits, it is not recommended that nucleic acid testing be performed immediately after same-day alcohol consumption; it is best to perform nucleic acid testing after the alcohol has been metabolized in the body. Especially in patients who have consumed large amounts of alcohol, it usually takes about 48 hours for the alcohol to be completely metabolized in the body, and it is recommended that nucleic acid testing be performed after the alcohol has been completely metabolized. If a nucleic acid test has already been performed after drinking and you are concerned about inaccurate results, it is recommended that a retest can be performed the next day to avoid missing the diagnosis. Before performing a nucleic acid test, in addition to not drinking alcohol, you should also avoid smoking, drinking, eating, chewing gum, etc. Nucleic acid testing is performed clinically, and the test sample is mainly obtained by means of a throat swab or nasal swab. Performing a nasal swab or throat swab after drinking or eating may induce nausea and vomiting. In addition to the issue of alcohol consumption, it is also important to take note of the need to carry valid documents for nucleic acid testing, to take precautions against epidemics, to wear a mask throughout the procedure, to pay attention to maintaining a social distance, and to cooperate with the doctor for testing.