Most of the nephrotic syndromes in pediatrics are primary, that is, the cause is unknown, but most of these types have a good prognosis; a few are secondary to systemic diseases, such as: allergic purpura, hepatitis B-related nephritis, systemic lupus erythematosus, rheumatoid, systemic bacterial infections, viral infections, drug kidney damage, poisoning, allergies and tumors, etc.; there is another cause of nephrotic syndrome in pediatrics Nephrotic syndrome in children has another cause, which is congenital or familial hereditary kidney disease, and the prognosis for this type is poor. Nephrotic syndrome can develop at any age, but it is more frequent in young people and children, and it is more likely to recur and be prolonged in boys than in girls. Generally speaking, some of the nephrotic syndromes with onset older than 8 years of age are more difficult to treat.