It is believed that every woman and even man in the world aspires to maintain a youthful and beautiful face forever, but age is a killing knife that is never merciful and always leaves a mark on the skin, causing people who are determined to seek beauty to suffer. Among the many traces of age, wrinkles must be a particular headache. Due to the natural decline of skin tissue aging, coupled with the inevitable ultraviolet radiation, the role of gravity and personal habits in daily life and other factors, the collagen, elastic fibers and other components of the skin gradually lost, the skin and thus appear folded, depression, the formation of aesthetic wrinkles. In response to the problem of skin aging, a series of maintenance and skin care methods have emerged, and the most convenient and immediate effect is the cosmetic injection. The most commonly used injectable drugs in hospitals are Botox and hyaluronic acid, both of which have very different principles of action and effects, and are used for the removal of dynamic and static facial wrinkles respectively. I. Dynamic wrinkle removal – Botox What is dynamic facial wrinkles? As the name implies, it is the wrinkle that will be produced only when the facial expression is active. The expression muscles in different positions will form the corresponding wrinkles when contracting, such as the forehead lines of the frontal muscles, the interbrow lines of the frowning muscles, the crow’s feet of the orbicularis oculi, the corners of the mouth and vertical lines of the lips of the orbicularis oris muscle, the cheek slashes of the zygomaticus major muscle and the upper lip square muscle, etc. The reason why Botox can remove dynamic wrinkles is that it can relax the muscles and prevent the expression muscles from over-activity, thus squeezing out the wrinkles. However, botulinum toxin is naturally metabolized by the body, and the effects usually last for about 4 to 8 months. However, it has been reported that the duration of the effect achieved after repeated injections after it has expired can be extended time by time. At present, the commonly used brands of Botox in hospitals are BOTOX and Henley, which are imported and domestic respectively. Second, the removal of static wrinkles – hyaluronic acid Static wrinkles, that is, facial muscles completely relaxed, that is, the face without expression will still appear wrinkles, usually due to the reduction of subcutaneous fat and the pull of gravity and the appearance of folds. Commonly, these wrinkles include lines, head lines, and even bags under the eyes. For these types of wrinkles, obviously Botox does not work at all, but hyaluronic acid, which is commonly used to fill the face and reshape it, can be effective. Hyaluronic acid, commonly known as hyaluronic acid, is a natural biomolecule that is widely found in the skin and is therefore well compatible with our own tissues after being injected into the skin. Hyaluronic acid not only fills in the depressions and folds of the dermis to make the face fuller, but also promotes the production of collagen in the dermis. However, the effect of hyaluronic acid is also limited and usually lasts for about 6 months to 1 year. The brands of hyaluronic acid commonly used in hospitals today include Restylane and Hyaluronic Acid. In addition, many high elastic modulus hyaluronic acids now have a face lift effect. It can quickly improve mild to moderate facial aging problems in a matter of minutes.