Repeated failure after IVF transplantation is a painful problem for patients and a problem for doctors. Currently, our center has the following clinical measures to prevent and treat “repeated transfer failures”: 1) Hysteroscopy to find and treat related uterine cavity problems such as adhesions, scarring, and inflammation; 2) Tubectomy or ligation for cases of hydrocele to prevent inflammatory exudation from the fallopian tubes from interfering with embryo implantation; 3) Assisted hatching of embryos by creating a trabecular surface on the zona pellucida to facilitate embryo hatching and attachment to the endometrium; and 4) Assisted hatching of embryos. 4. endometrial scraping, which stimulates the local immune response of the endometrium to easily accept embryos, and this procedure is usually done together with hysteroscopy; 5. active immunotherapy, which stimulates the induction of closed antibody to the Th2 system to prevent embryo rejection, etc.; in addition, some colleagues in China have already In addition, there are already some colleagues in China who are carrying out peripheral blood mononuclear cells (PBMCs) cavity perfusion and have also achieved some therapeutic results. In conclusion, we have more clinical countermeasures for repeated implantation failure, but what method should be used for a particular patient? It is necessary to communicate carefully with the doctor and choose carefully.