Generally high γ-glutamyl transpeptidase alone does not have clinical diagnostic significance, but needs to be combined with other related examinations, as well as medical history and clinical manifestations, etc. to determine the result clearly. The γ-glutamyl transpeptidase in serum mainly comes from hepatobiliary system, so the clinical examination result of high γ-glutamyl transpeptidase is mainly related to hepatobiliary diseases, but γ-glutamyl transpeptidase is also abundant in pancreas, so it is also seen in pancreatic diseases. 1, biliary tract diseases: common biliary tract obstructive diseases, such as primary biliary cirrhosis, sclerosing cholangitis, gallstone obstruction, etc., can lead to Biliary stasis and elevated serum γ-glutamyl transpeptidase content; 2, liver diseases: such as acute and chronic viral hepatitis, acute alcoholic hepatitis, chronic alcoholic hepatitis, drug hepatitis, cirrhosis, liver fibrosis, fatty liver and other liver diseases, can cause the results of high γ-glutamyl transpeptidase; 3, pancreatic diseases: such as pancreatitis, pancreatic tumors, etc., the serum γ-glutamyl transpeptidase content in patients The serum γ-glutamyl transpeptidase level can also be mildly increased; 4, other: for example, diabetes, myocardial infarction, rheumatoid and other diseases, can also cause γ-glutamyl transpeptidase elevation. In addition, the elevated serum γ-glutamyl transpeptidase level may also be caused by some bad habits, not diseases, such as staying up late, drinking alcohol, after taking certain drugs, etc. Therefore, there is no need to be too alarmed by this result. Therefore, there is no need to be alarmed by this result, and it is enough to continue to observe or improve other tests under the doctor’s instruction. If disease is ruled out, this result can serve as a reminder to pay attention to regular work and rest in daily life and drink alcohol in moderation.