The main cause of cryptoglomerulonephritis is due to infection or immune factors. People with thylakoid proliferative nephritis, immunocompromised people, smokers and other people are easy to induce cryptoglomerulonephritis. 1. Infection: for example, streptococcus and other bacterial, viral and protozoal infections. Pathologic changes may show widely different pathological types, including microscopic lesion type, thylakoid proliferative nephritis, sometimes resembling post-dissolving streptococcal infection nephritis, and a few cases may show more severe glomerulopathy. 2. Immune factors: its occurrence may be related to immunity, and the pathogenesis is the abnormal function of the immune system leading to glomerular immune injury. Cryptoglomerulonephritis can also be seen in other causes, it is recommended to follow the doctor’s instructions to carry out relevant examinations, with the help of doctors to clarify the causes, and targeted treatment or therapy.