Gluteal injections have some benefits for sciatica, however, they can also lead to worsening sciatica. Buttock injections are a relatively common clinical treatment that is faster acting and more effective in treating sciatica. However, in the case that the patient himself suffers from sciatica, once the injection site of the buttock injection is deviated, it may cause sciatic nerve damage, leading to more serious symptoms of sciatica. Therefore, for the treatment of sciatica, patients are advised to listen to the treatment advice of the attending doctor and consider whether to choose buttock injection. At the same time, patients must go to the professional departments of regular hospitals to treat their diseases and have their buttocks injected by professional injectors, so as to avoid physical injuries, such as damage to the sciatic nerve, caused by irregular operation.