Pityriasis rosea is a self-limiting inflammatory skin disease, generally 4-8 weeks can be self-fading, only a few patients will have a recurrence. Common causes of pityriasis rosea recurrence include skin irritation, infection, low immunity, drug factors, etc. 1, skin irritation: patients use overheated water for bathing, or use alkaline body wash and soap resulting in skin irritation. Some patients with sensitive skin initially occurrence pityriasis rosea that is related to skin irritation; 2, infection: virus, bacteria, fungi, spirochetes and parasites and other pathogens caused by infection can be one of the causative factors of pityriasis rosea, again infection may appear pityriasis rosea again; 3, low immunity: daily stay up late, daily exercise less, partial diet, etc., can cause the body low immunity, also may lead to pityriasis rosea Pityriasis recurrence; 4, drug factors: bismuth, metronidazole, omeprazole, BCG vaccine, hepatitis B vaccine and pneumococcal vaccine and other drugs may lead to the appearance of rash, can also be manifested as pityriasis rosea-like performance, after healing leave temporary pigmentation spot, again apply the suspected drug rash can recur; 5, other: long-term high tension, stress reaction serious, allergic body, etc., also easy to lead to pityriasis rosea recurrence. In order to avoid the recurrence of pityriasis rosea, should avoid the possible triggering factors, such as the choice of mild soap, body wash bath, control the water temperature, avoid stimulating the skin, daily attention to ensure sufficient sleep, improve the bad diet, appropriate exercise, etc.. After the rash appears, follow the doctor’s instructions for medication, such as topical glycolic lotion, glucocorticoid ointment or oral loratadine, cetirizine, etc. When the rash is widespread, it can be combined with ultraviolet light therapy.