Pityriasis rosea is a kind of inflammatory, self-limiting papulosquamous skin disease with rose-colored rash covered with bran-like scales, maculopapular rash as typical skin lesions. The course of the disease is usually 6-8 weeks, also have several months or even several years does not heal the person, but after healing generally does not recur. The initial lesions are isolated rose-colored pale red spots, then the lesions can rapidly expand to 2-3 cm in diameter, with clear borders, covered with fine scales, called prodromal spots or mother spots, often occurring on the trunk and proximal extremities. 1-2 weeks later, pale red rashes appear one after another, about the size of a fingernail cover, generally less than 2.0 cm in diameter, often oval, with thin scales covered with circled free edges inward, with the long axis parallel to the skin lines. The rash is generally distributed on the neck, trunk, and proximal extremities, often accompanied by varying degrees of pruritus. The etiology of the disease is unknown, self-limiting, and may be related to human herpes viruses HHV-6 and HHV-7, etc. The aim of treatment is mainly to reduce symptoms and shorten the course of the disease. Local topical application of glyburide lotion, oral antihistamines for obvious itching, and short-term small doses of oral glucocorticosteroids for severe or prolonged conditions, as appropriate.