C-reactive protein is usually elevated in bronchitis, especially when accompanied by cough, yellow sputum, fever and other clinical manifestations, and if the blood count is accompanied by a significant increase in total white blood cells, neutrophils and calcitoninogen, C-reactive protein will also increase. Macrolide antibiotics. The early use of antibiotics can lower the C-reactive protein as soon as possible to facilitate the control of clinical manifestations and shorten the course of bronchitis. Therefore, C-reactive protein in bronchitis is clinically significant as an indicator of infection, and it is usually elevated in severe bronchitis, especially in patients with fever.