The severity of chronic pancreatitis can be differentiated based on physical examination, imaging, endoscopy, and laboratory tests. 1. Physical examination. Severe patients will have abdominal pain, abdominal pressure, high fever, jaundice and even biliary colic. In less severe patients, the above symptoms may be mild. 2. Imaging examination. MRCP examination of severe patients shows scattered irregular dilatation of branch pancreatic ducts and irregular dilatation of the main pancreatic duct; CT examination shows irregular dilatation of the main pancreatic duct along with irregular changes in pancreatic morphology, and there may be pancreatic duct stones, and even peripancreatic exudation and blurred fat gaps may occur. 3. Endoscopy. In severe patients, ERCP examination shows obvious irregular dilatation of the main pancreatic duct. 4. Laboratory examination. Serum and urine pancreatic enzyme levels are abnormal in severe patients, with serum pancreatic enzymes higher or lower than normal and urine pancreatic enzymes higher than normal observed at consecutive multiple points. For the identification of the specific severity of chronic pancreatitis, it is also necessary to timely hospital visits, under the guidance of the doctor to identify, and follow the doctor’s instructions for treatment.