Colorectal cancer is one of the most common malignant tumors in China, and metastasis is its main feature and also a major factor affecting prognosis and outcome. The most common distant organ metastasis of colorectal cancer is liver, followed by lung, so will intestinal cancer metastasize to bone? The answer is yes, but the incidence tends to be low, with the probability of bone metastasis reported in the literature ranging from 6-10%. Among the sites of bone metastasis, the most common ones are vertebrae, pelvis and ribs, and often combined with liver and lung metastasis, which poses great challenges to treatment and efficacy. The early clinical manifestations of bone metastasis from bowel cancer include pain, hypercalcemia, pathological fracture, and spinal cord compression or nerve root compression when metastasis reaches the spine. Pain appears early and is not easily detected at the beginning, mostly as bone pain or radiating pain at the site of bone metastasis, and gradually becomes persistent pain, which may include radiating pain of lower limbs. For early diagnosis, CT or MRI examination, as well as serum tumor index examination are feasible. In addition, PET-CT examination is feasible to clarify the whole body condition in order to decide the next treatment plan. If the nature of the lesion is not clear, bone aspiration and pathological examination can be performed to clarify the nature and source of the lesion. The treatment of bone metastasis of intestinal cancer mainly includes systemic treatment and local treatment. Systemic treatment mainly includes nuclear therapy, chemotherapy and drug therapy. Nuclear therapy is effective in relieving bone pain and has a direct killing effect on lesions. Chemotherapy is more effective for primary foci, but less effective for bone metastases, and the indications for chemotherapy should be strictly controlled. Drug therapy can combat pathological osteolysis, hypercalcemia, reduce the probability of pathological fracture, and improve the quality of life of patients. Local treatment includes surgery and radiotherapy. Surgical resection is indicated to relieve complications, such as neurological symptoms due to spinal cord compression, and to treat pathological fractures. The appropriate surgical procedure is chosen according to the patient’s condition. Although metastases are not sensitive to radiotherapy, radiotherapy can benefit patients by relieving pain caused by metastases and inhibiting local progression of the tumor.