Four times painless hematuria in six months needs to be identified and treated for the cause. Common causes include kidney disease, urinary tract tumor, systemic disease, etc.. According to the specific cause of the disease to be drug treatment, surgical treatment, and so on. 1. Kidney disease: When kidney disease occurs, the glomerular filtration membrane is damaged, which causes red blood cells to enter the urine and form persistent painless hematuria. Such as glomerulonephritis, you can apply ACEI or ARB drugs, such as captopril, irbesartan, etc. to lower blood pressure and reduce urinary protein, and you can also apply glucocorticosteroids and cytotoxic drugs, such as prednisone, cyclophosphamide and so on. 2. Urological tumor: in the early stage of urinary tumor, the small blood vessels on the surface of the tumor body will rupture, which may lead to the symptom of painless hematuria four times in six months. Surgery is feasible, and radiotherapy and chemotherapy can be used as auxiliary treatment at the same time. 3. Systemic diseases: many systemic diseases may lead to painless hematuria four times in six months, such as hemorrhagic disease, leukemia and so on. Apply medication according to the cause of the disease. There may be other reasons for four times painless hematuria in half a year, so we suggest that the patient should go to the regular hospital in time, complete the examination to clarify the cause of the disease, and then give targeted treatment under the guidance of the doctor.