1. Is assisted reproduction IVF? Assisted reproduction technology mainly covers 2 major aspects, one is in vitro fertilization – embryo transfer, or IVF as we often call it, and the other is artificial insemination. One of them is the in vitro fertilization-embryo transfer technique which is relatively technical and medically and environmentally demanding, but it is not that everyone should go for it. The two are suitable for different people, there is no obvious good or bad. 2, what is the generation, two generation or even three generation IVF? Is the third generation IVF better than the first generation? The difference between IVF I and IVF II is that in IVF I the egg and sperm are combined freely in a Petri dish, relying on their own fertilization ability and nature’s natural selection principle, while IVF II is used for patients who have difficulty in fertilization or have an extreme lack of sperm, relying on external help to inject one sperm into one egg, and there is no big difference between the fertilization rates of the two. There is no significant difference in fertilization rates between the two, only that they target different patient groups and there is no question as to which technology is more advanced. Pre-implantation diagnosis (PGD) is a technique that analyzes the genetic material of embryos obtained from second-generation IVF technology, and is used for patients who are at risk of birth defects or have a family history of genetic defects. These three generations of technology are only based on the people based on their technical development stage, there is no scientific difference between more advanced, so for different patients to choose different means of pregnancy, there is absolutely no need for excessive intervention. 3. Is ovulation promotion the better the more follicles? Of course not. The number of follicles promoted is closely related to the ovaries and individual responsiveness to the medication. Some patients can get 20 eggs in one cycle and 15 in the next, it does not make much difference. Some patients get 30 eggs, while others get 7 or 8, and feel that there are so few. There is no need to be envious of so many. More eggs do not necessarily mean better egg quality, and we have experienced that patients with too many eggs tend to have more average egg quality. Generally speaking, about 10-15 eggs is the right number to do. This is less harmful to the patient, less risk of overstimulation, and in sufficient numbers to allow for fertilization and culture. Of course, some patients have poor ovarian function, so ovulation promotion is not a panacea, and it is impossible to promote many follicles, which requires a comprehensive understanding of the patient’s condition. 4. Why did I get 10 out of 20 eggs? Nowadays, many patients are overly concerned about this matter because they are under stress. Often, the number of follicles in the patient’s memory includes the number of small follicles, which is obviously for the number of dominant follicles. For example, if there are 20 eggs, there may be only 12 large follicles and another small follicles that are meaningless. Also a large follicle may not be 100% egg production, there are many factors including empty follicle syndrome, immature eggs, egg retrieval problems, etc. Therefore, there is no need to be obsessed. 5. I got 30 eggs, why should I freeze my eggs? In our clinic, our laboratory staff will consider freezing some eggs for some patients based on their own conditions, the number of eggs obtained and the quality of the eggs. This is a way to preserve fertility. For example, if 30 eggs are retrieved, the laboratory sees that the eggs are of good quality and recommends freezing 10 of them. Then 20 eggs are taken for fertilization and in most cases 2 will be transferred and 3 or 4 will be frozen. If this is not successful, frozen embryos can be used. There are cases where the fertilization of all 20 eggs may be poor, and then it will be discovered whether it is a sperm problem or an egg problem, and then with frozen eggs there will be a change in the means of assisting the pregnancy or an additional aid. This is a protective measure for the patient. Of course, egg freezing technology is not as sophisticated as embryo freezing technology and the attrition of freezing and thawing is relatively high. However, this does not mean that the technology should be abandoned. For example, if all 30 eggs have formed embryos and the patient has had one or two children, what happens to the 10 or so embryos that are still frozen? This is an absolute waste of valuable egg resources. 6. I have not been pregnant for 6 months. Can I do IVF? Many patients are under pressure because of their age, length of marriage, and other factors. They are often anxious to do IVF after less than a year of contraception, but in fact, the examination reveals no tubal problems or ovulation problems. Often anxiety has an impact on the success rate of pregnancy and constantly superimposes this pressure, causing tension in the couple’s relationship. Unless problems such as fallopian tube failure, ovulation disorders, poor ovarian function, poor sperm quality and other problems that clearly require assisted conception are found during the examination, we do not recommend patients to choose assisted reproduction for pregnancy in too much of a hurry. You can start with ovulation monitoring, ovulation promotion and guidance on intercourse. Even after psychological counseling or life guidance, many people can get pregnant on their own. 7.I have bad fallopian tubes, do I need to have surgery? Tubal imaging can only reflect some of the problems of the fallopian tubes, only from a physical point of view, such as morphology and patency, and can only guess whether there are problems such as pelvic inflammatory disease, but there is no way to know its actual function. As to whether the tubal problems need surgical treatment, it is recommended to take the film to the surgeon at the regular hospital to find out, they will give a more objective advice and can give some treatment during the surgery. 8.I have a bad lining, should I take Tocopherol? No. Tonic is not a holy grail medicine. There are many factors that contribute to poor endometrium: post-surgical damage, lack of endometrial receptors, insufficient hormone levels, congenital dysplasia, etc. It is not always effective to rely solely on estrogen supplementation. However, because of the limited means of testing, we can only try to improve the situation with some pharmaceutical intentions. The practice of medicine is very often an empirical treatment, and individual differences, treatment methods, and available technology all dictate that there can be no panacea.