Lower extremity venous thrombosis drug therapy, mainly including anticoagulation therapy, thrombolytic therapy and promotion of venous return and other treatments.1. Anticoagulation therapy is the basis of lower extremity venous thrombosis drug therapy, and is also the most important treatment means. The common anticoagulant drugs mainly include warfarin, common heparin and low molecular heparin. There are also some new oral anticoagulants, such as rivaroxaban and dabigatran, etc. 2. Thrombolytic therapy. Thrombolytic therapy is mainly to dissolve the thrombus by strengthening the action of fibrinolytic enzymes to produce fragmentation of the thrombus. The common thrombolytic agents mainly include urokinase, streptokinase, tissue-type fibrinogen activator. 3.Therapy to promote venous return. These treatments are adjuvant therapies to the pharmacological treatment of venous thrombosis, mainly by promoting venous reflux, eliminating the symptoms of swelling and slowing down the further development of venous thrombosis.