Oculomotor spasm is an involuntary twitching of the muscles around the eyes, which is what we normally call eyelid twitching. Common causes of oculomotor spasms are excessive eye use or strain, mental overstrain, etc., and are limited to upper or lower eyelid twitching. These symptoms are mainly a manifestation of nerve endings irritation, so the symptoms are often confined to one side of the upper or lower eyelid and occur occasionally. Most patients can recover with stress relief and proper rest. However, in a minority, the facial nerve fibers innervating the eye muscles are irritated by inflammation or vascular compression, when each twitch lasts for a few seconds, with a tendency for the condition to worsen in stages, recurring episodes, or easily triggered by stress, progressing from simple upper or lower eyelid fluttering to upper and lower eyelid twitching, or even developing into involuntary twitching of the muscles on the same side of the face. Extreme cases of twitching may even cause difficulty in opening the eyes, facial pain, affecting vision, speech and sleep, and may have interictal periods lasting from several days to several months, seriously affecting the patient’s social interactions and life. Treatment of ocular myasthenia 1, drug treatment refers to the clinical often use some sedative and tranquilizing drugs to relieve mental tension, so as to achieve the purpose of relieving symptoms. 2, Botox injection treatment is the use of botulinum toxin to block the acetylcholinergic release of the facial nerve at the location of the eye muscle twitching, thereby blocking the transmission of abnormal nerve electrical signals, so that the eye muscle spasm is released. 3.Surgical treatment is mainly for patients with clear facial nerve compression lesions, and the treatment purpose is achieved by surgical removal of the compression. Drug treatment is mainly symptomatic and the effect is uncertain. The effect of surgical treatment is good, but only if the location of facial nerve compression and the compression object can be confirmed before surgery; at the same time, surgical treatment is invasive after all, and there are certain risks. Botulinum toxin injection treatment is a non-invasive outpatient operation, and the effect is maintained for about 3 to 6 months after a one-time botulinum toxin injection, so the effect is certain and convenient, and it is easy to be promoted clinically.