I often have kidney disease friends ask me: “My hematuria and proteinuria are not serious, do I need kidney puncture?” 1, you can take a look at my article, kidney puncture – the golden indicator of kidney disease diagnosis. 2, the performance of laboratory tests of kidney disease is almost always hematuria, proteinuria; clinical performance of edema, back pain, etc.. But the actual pathology of the kidney is a thousand miles away, the degree of hematuria and proteinuria and the actual damage and prognosis of the kidney are not parallel, so kidney puncture is very important, kidney pathology can let us understand the actual situation of the kidney. 3.It is not good to evaluate your medication before the diagnosis is confirmed by kidney puncture. If it is a light nephritis, the treatment can have Chinese and Western medicine and other treatments. But if your kidney disease is more serious and urgent, the treatment must be active. Application: hormones, cytotoxic drugs, etc. 4, especially young people, combined with hypertension, decreased kidney function, 24-hour urine protein quantification greater than 1g, severe edema, intermittent carnitic hematuria, etc., must consider kidney penetration. The indicator of blood creatinine is not sensitive and is not used as the main indicator of renal puncture.