Mole spotting is the removal of a mole by laser, freezing, or medication, which can cause irritation to the top layer of skin where the mole is present, resulting in localized tissue damage. Usually, you can rub mupirocin ointment, recombinant human epidermal growth factor gel and other medicines as prescribed by the doctor after mole spotting. 1. Mupirocin ointment: it can play the role of antibacterial and antiseptic, effectively prevent secondary infection and avoid local redness and swelling. 2. Recombinant human epidermal growth factor gel: it can promote DNA synthesis in the process of traumatic tissue repair, with the effect of accelerating the generation of traumatic tissue and proliferation of epithelial cells, which can shorten the healing time of the wound. It is recommended to consult with professional doctors for relevant matters after mole spotting, and use medication under doctors’ guidance, and strictly prohibit unauthorized use of medication.