Age is an important independent factor affecting fertility, and research data suggest that fertility is highest in both men and women who marry between the ages of 24 and 25. It is well established that fertility declines with age, especially in women, and that fertility begins to decline rapidly after age 35. Age at marriage, years of marriage, age at first sex, age at menarche, number of sexual intercourse per week, history of abortion, male partner’s exposure to radioactive substances, history of hot work for both sexes, history of oral contraceptives and history of smoking and alcohol use all have an impact on conception. Some studies have shown that smoking and alcohol consumption have an effect on reproductive function. Due to various psychological pressures from society and family, infertility patients inevitably have certain anxiety, depression, hostility and other psychological problems, especially in poor and backward areas, and the economic burden caused by long-term treatment is also a psychological stress response. Common psychological reactions of infertile women are reduced self-worth, frustrated self-esteem, repression, introversion, ambivalence, lack of recognition of the psychological relationship with infertility, and reluctance to receive psychological treatment. Studies have shown that infertile women have significant differences in interpersonal relationships, depression, anxiety, and hostility compared to normal pregnant controls, suggesting that infertile women have more subjective symptoms and self-conscious discomfort. It is important for infertile patients to sympathize and understand that social pressure from life and other sources often brings psychological burden to infertile couples, and this psychological burden often makes it more difficult for patients to conceive, thus forming a vicious circle that further impairs the ability of infertile patients to conceive, and under the doctor’s explanation to eliminate concerns and build confidence in treatment, the principle of treatment is to treat the cause.