The spleen enlargement caused by cirrhosis cannot be restored to normal, because after cirrhosis of the liver, the blood vessels in the liver are narrowed by pressure, and the blood flow back to the liver is poor, causing spleen stasis, which will lead to spleen fibroplasia and gradual enlargement over time. The enlarged spleen is followed by hyperfunction, and the spleen will swallow too many blood cells, causing a decrease in white blood cells and platelets in the blood. The enlarged spleen cannot be restored to normal by medication. If the complications caused by splenomegaly are more serious, such as high blood cell reduction, infection or bleeding may occur, which can only be treated by spleen amputation or spleen embolization.