Cat-scratch disease is an acute infectious disease that occurs as a result of contact with cats and was first described in 1950, with adolescents and children being the preferred age for cat-scratch disease. Clinical manifestations are skin lesions and localized lymph node enlargement. The main findings are lumps in superficial areas such as the neck, axillae, and upper extremities and unexplained superficial lymph node enlargement. Cat-scratch disease is a sporadic, human-animal infectious disease, 80% of which is associated with cat-scratch injuries. The pathogen is a Gram-negative, slender, polymorphic rod-shaped bacillus, and cats are the main reservoir hosts with a high carrier rate, usually in the oropharynx of healthy cats, transmitted by scratching or biting. Patients all have a history of close contact with pets such as cats. Long-term contact with small animals inevitably involves skin scratches and licking and biting, and some minor skin injuries at the beginning are not enough for parents to pay attention to. The lump is found with clear borders, hard texture and no local pressure pain. There may be low fever or no fever. Laboratory tests for blood count, sedimentation, and CRP are normal. The clinical presentation of cat-scratch disease is usually mild, but severe systemic disease may occur in some immunocompromised children, especially in infants and young children.