Antithyroid medication for hyperthyroidism Hyperthyroidism (hyperthyroidism) is a common thyroid disorder that can occur at all ages and, if left untreated, can cause serious damage to all body systems and can affect the growth and development of adolescents, as well as pregnancy and breastfeeding in women of childbearing age. There are many causes of hyperthyroidism, the most common one is autoimmune hyperthyroidism (Graves’ hyperthyroidism). With the development of medical science, the treatment of hyperthyroidism has made great progress, and anti-thyroid medication is one of them. 1, anti-thyroid drugs are methimazole (Tabazole, Sage) and propylthiouracil. The remission rate varies from 30% to 70%, with an average of 50%. 2.Drug therapy is applicable to all kinds of hyperthyroidism patients without contraindications, the treatment method is simple, but the course of treatment requires 1 year to 1.5 years, the recurrence rate is higher, and at present, the anti-thyroid medication has gradually become an auxiliary method before or after surgery or iodine-131 treatment. 3. The effect of anti-thyroid medication appears after 4 weeks, and the dosage can be gradually reduced to the minimum maintenance dosage after the normalization of thyroid function. 4.Discontinuation of medication should be decided according to the condition, the level of thyroid hormones in laboratory tests, the course of treatment and other factors. Some literature suggests that a high level of thyroid antibodies (TRAb) is associated with a higher relapse rate. However, I do not believe that this should be used as a basis for stopping the drug. 5, the side effects of anti-thyroid drug treatment include rash, itchy skin, leukopenia, granulocytopenia, toxic liver disease and vasculitis, etc. Leukocytes and liver function should be checked before using the drug. During the treatment period, attention should be paid to the clinical abnormalities, and leukocytes and liver function should be rechecked regularly. 6, granulocyte deficiency is a serious complication of antithyroid drug treatment, the onset of acute, often manifested by high fever, sore throat and other symptoms of acute infections, timely detection of white blood cells is the key to a clear diagnosis. Granulocyte deficiency should be treated urgently, delayed treatment can be life-threatening. Compound iodine solution (Lugol’s solution) and adrenocorticotropic hormone are the key medications, which need to be accompanied by strong leukocyte-boosting drugs, heart rate control and anti-infection, supportive therapy and other measures. Once granulocyte deficiency is present, correction should be followed by iodine-131 therapy.