Peripheral arterial disease (PAD) is a disease that causes insufficient blood flow to the limbs due to arterial stenosis. In recent years, with the increasing aging of the society’s population, the incidence of peripheral artery disease has been increasing year by year, reaching 10% in people over 60 years old and 20% in people over 65 years old with atherosclerosis-occlusive disease, and all diabetic patients with more than 5 years of history have different degrees of peripheral vascular disease. However, little is known about peripheral artery disease, and even some non-specialists often misdiagnose and miss the diagnosis. For example, typical intermittent claudication is often treated as lumbar disc herniation, mesenteric artery embolism is often misdiagnosed as intestinal obstruction, acute pancreatitis, and other general acute abdominal conditions, and some patients with long-term hypertension actually suffer from renal artery-type aortitis, among others. This directly leads to many patients losing the best opportunity for surgical treatment, or even losing the opportunity for treatment altogether. Many people may think that atherosclerosis is only the hardening of the coronary arteries of the heart, which may cause coronary heart disease, heart attack, etc., or cerebral arteriosclerosis causing cerebral infarction, hemiplegia, etc., but they do not know that atherosclerosis is a disease that involves the arteries of the whole body, which not only involves the cardiovascular and cerebral vessels, but also involves the internal organs and limb arteries, which can still bring about disabling and fatal consequences. If atherosclerotic lower limb arteries have atheromatous plaques or detached wall thrombi, they can block the distal arteries with blood flow, which can be disabling or life-threatening if not treated in time. The following are the main risk factors for lower extremity atherosclerosis: diabetes, smoking, high blood pressure, high cholesterol, unhealthy eating habits, lack of exercise, excessive alcohol consumption, chronic weight bearing, and overweight. How can you reduce your risk of lower extremity atherosclerosis occlusive disease? The best thing to do is to prevent it. There are several ways to reduce your risk of lower extremity atherosclerosis occlusive disease, which include the following: don’t smoke, eat healthy, exercise regularly, maintain a healthy weight, avoid stress, keep your blood lipids and blood pressure normal, avoid excessive alcohol consumption, physical training, etc.