Atherosclerotic occlusion (ASO) is a common complication of atherosclerosis, the most common peripheral vascular disease in middle-aged and elderly people, due to the continuous expansion of atherosclerotic plaques and secondary thrombosis, resulting in arterial luminal narrowing or even occlusion, the affected limb chronic or acute ischemic symptoms, the typical symptoms of intermittent claudication, accompanied by cold limbs, low skin temperature, numbness, acidity, fatigue, tingling, dorsal foot arterial weakening, followed by pale, yellow or purple skin, dry skin, pale, yellow or purple skin. The typical symptoms are intermittent claudication, accompanied by limb coldness, low skin temperature, numbness, acidity, fatigue, tingling, weakening of dorsal artery of the foot, followed by pale, yellowish or purplish skin, dry skin, desquamation, shedding of sweaty hairs, deformation of toenails and other nutritional disorders, and in severe cases, there will be ulcers, infections or gangrene, with severe pain, and in advanced stage, there are more secondary thrombosis, or atherosclerotic plaques dislodgement, which will block the lumen of the arterial tubes, and rapidly appearing high Widespread gangrene of limbs and life-threatening. In recent years, with the continuous improvement of our people’s living standard, irrational dietary structure and the aging of the population, the incidence of ASO has shown a significant upward trend, and it has become one of the main diseases affecting the quality of life of middle-aged and old people as well as endangering their lives.Since 2001, the author has adopted the empirical formula (Ginkgo blood-vitalizing formula) to treat this disease, and has achieved remarkable therapeutic effect, which is summarized as follows for the benefit of the fellow patients. 1, clinical information 1. 1 general information of this group of patients a total of 156 cases, of which 117 cases of male, female 39 cases; the oldest 87 years old, the youngest 54 years old, the shortest course of 19 days, the longest 17 months,. Among them, 13 cases were 54-64 years old, 121 cases were 64-74 years old, and 22 cases were over 75 years old. There were 119 cases of hypertension, 61 cases of coronary artery disease, and 15 cases of thromboembolic vasculitis (TAO). 1.2 Diagnostic criteria refer to the diagnostic criteria of “Vascular Committee of All-China Association of Traditional Chinese Medicine” in 1992 <>; (1) the age of onset of the disease is over 40 years old, or there are systemic arteriosclerotic lesions; (2) there is a typical cold pain or burning sensation in the toes, soreness and distension of calves, intermittent claudication, and static claudication, with a feeling of coldness or burning sensation in the toes, and a feeling of pain in the calves. intermittent claudication, resting pain, aggravated at night; limb skin color dark red, bruising. Muscle atrophy, weakening or disappearance of pulsation of large and middle arteries of the limbs, dry gangrene at the toe end, severe pain and other symptoms; (3) limb and cerebral hemogram suggests that arterial pulsation blood flow is reduced, and arterial elasticity decreases or disappears. Color ultrasonography suggests atherosclerosis or occlusion to confirm the diagnosis. 2.Treatment Ginkgo blood formula basic composition: 30g of ginkgo biloba, 30g of hawthorn, 30g of rhodiola rosea, 30g of danshen, 30g of red peony, 20g of yuanhu, 15g of hyssop, 15g of peach kernel, 15g of safflower, 15g of leech, 30g of dillon, 10g of panax quinquefolii, 15g of hyacinthium and 4g of gecko, one payment per day, decocted into water to be divided into two servings, 15 days for a course of treatment, hypertension, coronary heart disease. Add its regular treatment drugs; long illness gas deficiency plus ginseng, astragalus, atractylodes, poria; fear of cold limbs cold people plus epiphyllum, cinnamon sticks, etc.; pain is intense, sleepless nights plus the system of milk did not, rice shells or with analgesic and sedative drugs; heat and toxicity blazing limb ulcers plus detoxification and stasis pills. (Composition: 50g of Erhua, 12g of rhubarb, 20g each of Dilong, earthworm, leech, frankincense, 10g each of myrrh, whole worm, mountain beetle, 3 centipedes, 30g of Yuanhu, etc.). 3. Efficacy standards and results 31 The efficacy standards refer to the standards of <> and <> promulgated and implemented by the State Administration of Traditional Chinese Medicine in 1995. Cure: pain in the affected limb disappeared, skin color and temperature returned to normal, sores healed, walking freely, or tarsal vein could be touched. Improvement: The pain basically disappears, but the gait activity cannot be sustained, and the scope of the sore is reduced. Unhealed: the pain cannot be controlled, the ulcer cannot heal, or continues to develop proximally. 32 treatment results cure: 79 cases, improved 53 cases, not healed: 24 cases, the total effective rate of 84. 62%. 4.Typical case Yang Moumou, male, 73 years old, retired employee, on January 14, 2004 came to the clinic. The patient in 3 months ago appeared double lower limbs acid discomfort, toe cold, numbness, gradually aggravated, intermittent claudication, followed by the right 4, 5 toes necrosis, ulceration. Local treatment was ineffective, and she was referred by a local hospital doctor to seek treatment. At that time, he saw coldness and chills in both lower limbs, intermittent claudication (less than 100M), pain at night, purple color of lower limbs, low skin temperature, dryness and flaking, muscle atrophy, deformation of toenails, dorsum of the foot was red and swollen, the right 4 and 5 toes were ulcerated, with foul smell, and the dorsal arteries of the foot and posterior tibial arteries had disappeared from the pulsation. Ultrasound: atherosclerosis of both lower extremity arteries, lumen occlusion, blood flow interruption. Laboratory tests: plasma total cholesterol (TC) 8.13mmol / L (normal value 2.33mmol / L ~ 5.69mmol / L), triglyceride (TG) 7.61mmol / L (normal value 0.565mmol / L ~ 1.695mmol / L), red blood cell count of 3.8 × 1012 / L, leukocyte count of 15 × 109 / L Neutrophils 87%, lymphocytes 13%. His body temperature was 38.10 C. He was diagnosed with atherosclerotic occlusive disease. He was hospitalized and given traditional Chinese medicine: 30g of hawthorn, 30g of ginkgo biloba, 30g of rhodiola rosea, 30g of danshen, 30g of red peony, 20g of yuanhu, 15g of hyssop, 15g of peach kernel, 15g of safflower, 15g of leech, 30g of dillon, 10g of panax ginseng, 15g of hyoscyamus, 4g of gecko, 12g of frankincense, 12g of myrrh, and 20g of rice husk, which was decocted in water and divided into two times daily. 8 million units of static point to control infection, 7 days after the pain relief, dorsal foot redness and swelling subsided, sleep at night, symptoms improved, only poor diet, stop using antibacterial agents, the front to go to the frankincense 12g, 12g of myrrh, plus atractylodes macrocephala 20g, 15g of hen’s inner gold, following the service for 7 days. After 45 days of hospitalization, the pain of the affected limbs disappeared, the skin color and temperature were basically normal, and the intermittent claudication disappeared (no obvious discomfort when walking slowly for 1000M). The necrotic right 4 and 5 toes were detached, the stump was crusted, and the dorsalis pedis artery was palpable, and the patient was clinically cured. She was discharged from the hospital, and was advised to take Antidote and Resolve Blood Stasis Pill and Activate Blood and Penetrate Blood Pill (both prepared by Anyang City Vasculitis Hospital), 3 times a day, 5g each time, after meals. After half a year, he was rechecked. Symptoms did not recur. 5.Discussion Atherosclerotic occlusive disease (ASO), is atherosclerotic lesions involving peripheral arteries and lead to chronic occlusion of a disease, is a part of the systemic atherosclerosis, is currently believed to be associated with hypertension, hyperlipidemia, obesity, hyperglycemia, smoking, etc., resulting in dyslipidemia and arterial endothelial cell damage caused by the vascular wall of the permeability of the blood vessel wall, so that lipids migrate to the arterial endothelium, migration of lipids cause mononuclear cells in the blood. Lipids cause blood mononuclear cells and smooth muscle cells in the arterial intima to enter the intima, phagocytosis of lipids to form foam cells and necrosis, disintegration, and stimulation of intimal fibrous tissue proliferation, leading to atherosclerotic plaque formation and thickening of the arterial intima. With the increase of atherosclerotic plaque, coupled with secondary bleeding and thrombosis at the plaque, gradually leading to lesions at the arterial lumen narrowing and occlusion, thus causing a series of clinical manifestations of ischemia of the affected limbs. According to Chinese medicine, this disease belongs to the category of “gangrene”, the reason for this is that people’s living standard is improving, they want to eat spicy and thick food, and their diet structure is unreasonable, coupled with the aging of the population, the zongqi of the old age is declining, and the lack of qi will weaken the role of promoting, warming and qi, slowing down the flow of blood, making it difficult to maintain the normal operation of the blood and the fluid, and the lack of qi can not promote the blood flow, which will lead to a series of clinical manifestations of ischemia. When the qi is deficient, it is difficult to maintain the normal operation of blood and fluid, and when the qi is deficient, there is no way to push the blood to move, and the blood does not move smoothly, resulting in stagnation of blood and stagnation of meridians and channels. Ginkgo biloba, hawthorn, danshen, rhodiola rosea, yuanhu, hyssop, peach kernel, safflower, leech, dilong, tuyuan, gecko, panax ginseng and other medicines have the efficacy of breaking the blood stasis, activating blood circulation and promoting the flow of qi, clearing up collaterals to alleviate pain, and the main active ingredient of ginkgo biloba is ginkgo biloba flavonoids, which has the effect of vasodilating blood vessels, inhibiting platelet activating factor, antioxidant and regulating blood lipids, and it can obviously improve the effect of HDL(high density lipoprotein). It can significantly increase high-density lipoprotein (HDL), fight against platelet activating factor, reduce blood viscosity, plasma cholesterol, blood fibrinogen, improve the ratio of plasma cholesterol and phospholipids, and at the same time, inhibit collagen-induced platelet deformation and slow down the maximum aggregation of platelets to inhibit the formation of blood clots. Rhodiola rosea and Panax ginseng are rich in unsaturated fatty acids, which can remove free radicals in the body, and Yuanhu, hyssop, peach kernel, safflower, leeches, danshen, dillon, earth yuan, gecko and other medicines together, with very good effect of lowering blood viscosity, blood lipids, and cholesterol, which is used in the treatment of this disease with very good results.