Mycoplasma infections caused by colds are mainly treated with symptomatic and anti-mycoplasma therapy at this time. Generally for irritating, persistent cough caused by mycoplasma, glucocorticoids, such as budesonide nebulizer and α chymotrypsin, can be used for nebulized inhalation to relieve symptoms. In addition, antimycoplasma can be treated with macrolides, such as the choice of azithromycin, erythromycin, methomycin, and memantine, etc. If necessary, quinolones, such as levofloxacin, lomefloxacin, and ciprofloxacin, can be combined. The treatment period can be 1-2 weeks with drugs depending on the condition. In some patients, if the condition is mild and the infection is not serious, it can be self-healing in about 2 weeks without special treatment.