Laser treatment will damage the local skin, female patients with acromegaly need to pay attention to bed rest, strictly prohibit sex, eat a balanced diet, but also need to pay attention to perineal hygiene, to prevent infection. 1. bed rest: after the laser treatment need to bed rest for 3 days, try not to stand for a long time, to prevent local congestion, affect the skin healing. 2. Sexual intercourse is strictly prohibited: Sexual intercourse is strictly prohibited during the treatment of acromegaly to prevent cross-infection and affect the effect of treatment. 3. Eat a balanced diet: patients need to pay attention to a balanced diet after laser treatment, more intake of high-quality protein, to promote the recovery of the wound. 4. Pay attention to hygiene: patients need to pay attention to local hygiene after laser treatment, keep the affected area clean and dry, and regularly change underwear to prevent infection and affect the treatment effect. It is recommended that patients actively cooperate with the doctor’s treatment, regular follow-up.