Prostatitis is a common disease among young and middle-aged men and is mainly characterized by urination and painful symptoms, leading to a reduced quality of life for patients. The most important issue for couples who want to have children after marriage is whether prostatitis affects fertility. The author has reviewed a lot of domestic and foreign literature and combined it with his long term clinical practice that prostatitis is not the culprit of male infertility. The causes of male infertility are varied and involve genetic disorders, reproductive tract infections and immune factors. At present, only a small percentage of male infertility can be identified with a clear cause, while 60-75% of patients cannot find a causative factor related to male infertility (primary infertility). However, to date, there is not enough evidence to prove that prostatitis causes infertility. The actual fact is that we have found many patients with recurring chronic prostatitis for many years who are still having a lot of fun at home. The majority of chronic prostatitis does not have bacterial or other pathogenic infections or inflammation of the seminal tract, and therefore does not affect the quality of semen (sperm density, sperm motility, sperm morphology, etc.). The chronic prostatitis can be completely controlled after regular and systematic medication. Even if the harmful components in the prostatic fluid (prostatic fluid is an important part of semen, accounting for about 1/3 of the latter) interfere with sperm quality and affect fertility, it is short-lived (weeks – months), mild and recoverable. Moreover, sperm are only in contact with prostatic fluid for a short period of time after ejaculation, and highly mature sperm are also able to withstand the general inflammatory environment and maintain fertilization. Now, there is no basis to suggest that prostatitis is an infectious disease (urethritis, etc.) and clinical observations have not found that prostatitis in the male partner affects the function of the female reproductive system or fertility. The actual fact is that there are a number of unrelated illnesses (infertility, sexual dysfunction, etc.) and manifestations (seminal fluid non-liquefaction, little, weak, deformed sperm, etc.) that some medical doctors will label as “prostatitis” and “bombard” them. Now clinically urological male doctors determine whether prostatitis has affected fertility, mainly depending on the following two conditions: 1, whether there is prostatitis (symptoms + routine prostate examination leukocytes exceed the standard); 2, whether the semen leukocytes exceed the standard, if necessary, semen bacterial culture can be done. If you consider that prostatitis may have affected fertility, you can treat prostatitis first and observe the improvement in semen quality and fertility after the inflammation is controlled. In conclusion, you can’t equate prostatitis with male infertility, and you don’t have to be overly worried, pessimistic and disappointed, carrying a heavy burden of thought, these people can still get married and have the same chance of having a baby as normal people.