Red bloodshot and slightly painful eyes may be caused by eye fatigue, conjunctivitis and keratitis, and can be treated with medication and other methods. 1. Eye fatigue: long-term excessive use of the eyes, it is easy to appear the phenomenon of eye fatigue, leading to eye congestion, resulting in eye redness and micro-pain. You can use polyvinyl alcohol eye drops for treatment, to replenish moisture for the eyes, has the effect of relieving eye fatigue, so as to relieve the symptoms of eye redness and pain. 2. Conjunctivitis: Bleeding in the eyes when suffering from conjunctivitis is due to the conjunctiva being infected by bacteria, which will lead to dilation of blood vessels in the conjunctival tissues and obvious congestion, thus resulting in red bloodshot and slight pain in the eyes. You can use levofloxacin eye drops for treatment to inhibit the activity of bacterial DNA rotamase, thus inhibiting the replication of bacterial DNA, thus relieving the symptoms of red eyes and slight pain. 3. Keratitis: due to the local inflammatory reaction to stimulate the corneal epithelium and the mucous membrane around the cornea, capillary dilatation occurs, resulting in intravascular blood filling, thus the symptoms of eye redness and pain. Tobramycin eye drops can be used for treatment, the main effect is to be able to inhibit the protein synthesis of bacteria, thus killing bacteria, thus relieving the symptoms of eye redness and slight pain. If the patient’s eyes are red and painful, it is recommended to go to the hospital in time to find out the cause of the disease and then targeted treatment.