Pearl rash usually refers to pearly penile papules, get rid of pearly penile papules generally does not exist small trick, clear disease if there is no discomfort symptoms, you can do without treatment, but if you want to get rid of recommended to the regular hospital to seek medical advice, choose the appropriate way to target treatment. Pearl penile papules can be considered caused by local irritation, such as long foreskin, foreskin coronal infection and other factors, the need to apply drugs for treatment, but also through surgery or physical therapy to get rid of: 1, drug treatment: If pearl penile papules exist local redness, swelling, itching, can be under the guidance of the doctor with cleansing lotion with physiological saline ratio after the affected area soak, if necessary, local application of Mupirocin ointment to help sterilization and anti-inflammatory, eliminate uncomfortable symptoms; 2, surgical treatment: If the pearly penile papules are induced by the prepuce, circumcision can be performed to remove the foreskin, reduce local dirt stimulation, and thus alleviate the symptoms; 3, physical therapy: If you feel that pearly penile papules affect your daily life, you can also get rid of them through laser treatment, electrocautery treatment and cryotherapy. The laser treatment can make the tissue of pearly penile papules necrotic, thus promoting skin regeneration and improving the lesions, while cryotherapy uses low temperature to make the lesion cells damaged and fall off, in order to achieve the purpose of treatment. However, it should be noted that laser therapy, electrocautery and cryotherapy carry certain risks. In addition, patients need to pay attention to personal hygiene, so that every day before going to bed with water to fully wash the affected area, especially before and after sex, must be clean, change underwear every day, avoid scratching, avoid spicy and stimulating food and greasy food, quit smoking and alcohol, can help relieve discomfort.