Recently, a 23-year-old female patient came to the hospital with “loss of cold sensation in the left lateral body and weakness in the right limb”, MRI suggested a high cervical spinal cord lesion. The patient had a transient lack of cold sensation in the right lower extremity and transient abnormal pruritus in both upper extremities 2 years ago and 1 year ago, which were not treated specifically and resolved on their own within a week or so. These are often overlooked or even misdiagnosed by the public or physicians, resulting in delays or delays. Therefore, it is appropriate to be vigilant when the following conditions occur: 1) The presence or previous experience of symptoms suggestive of MS, including: fatigue or weakness, loss of vision, diplopia, abnormal sensations on the face or body (numbness, itching, pain or loss of pain and temperature sensation, etc.), unsteadiness in walking, poor coordination, and abnormal urination and defecation. These symptoms may be mild or disappear quickly; 2) physical examination or for some reason an MRI scan of the brain or spinal cord reveals single or multiple lesions, the nature of which cannot be clarified or demyelinating disease is suspected; 3) someone in the family has been diagnosed with MS; in the above cases, we recommend that you see a neurologist for consultation and evaluation.