1, penicillin: safer, including broad-spectrum penicillin such as piperacillin. Oral, intramuscular and intravenous injections are available for pregnant women. Warning: Use according to the recommended dose, do not overdose. 2, erythromycin: similar drugs also have leucovorin, roxithromycin, etc., large molecular weight, not easy to reach the fetus through the placenta, penicillin allergy can be used, chlamydia, mycoplasma infection preferred drugs. 3.Pioneeromycin: current information has no teratogenic effect. Tips: Dangerous antimicrobials report card Some antimicrobials are not recommended for pregnant women because of their different toxic side effects, the common ones are: ① Tetracycline: can cause yellow-brown pigmentation of teeth, or stored in the fetal bones, and can also cause acute fatty liver and renal insufficiency in pregnant women. ②Gentamicin: Kanamycin and Xiaonomycin can cause fetal auditory nerve and kidney damage. ③Chloramphenicol: cause gray baby syndrome. ④Compound Synthroid, synthroid tablets, can cause yellow pox in newborns, and also antagonize folic acid. ⑤ Furazolidine: often used in women with urinary tract infections, and should be used with caution because it can cause hemolysis. Vancomycin: Although the risk to the fetus has not been reported, it has nephrotoxic and ototoxic effects on pregnant women. (7) Ciprofloxacin, haloperidol, orfloxacin: irreversible arthritis has occurred in dog experiments. (8) anti-tuberculosis drugs: consider the pros and cons when using size according to their own situation please ask your doctor. ⑨ anti-mycotics: clotrimazole, mycobacterium, ashwagandha, preferably not used in pregnant women. ⑩Anti-viral drugs: not advocated for pregnant women. 4.Metronidazole: insecticide, treatment of trichomonas infection, advocate not to use in early pregnancy. 5.Spiramycin: treatment of Toxoplasma gondii infection, no adverse effect on the fetus. 6, anthelmintics: animals have teratogenic effects, should be used with caution. 7.Digoxin: cardiac drug, easy to pass through the placenta, no obvious adverse effects on the fetus, and can be used by pregnant women with heart failure. 8, β-blockers: there are reports of fetal growth retardation. 9, antihypertensive drugs: there is a clear teratogenic effect of pregnant women are prohibited angiotensin-converting enzyme inhibitors, such as captopril, angiotensin II receptor antagonists such as coxsartan, other types of antihypertensive drugs such as calcium antagonists (on behalf of the drug heart yodeling, there is the possibility of causing a reduction in uterine blood flow, diuretics near term administration can cause neonatal thrombocytopenia should be used with caution, acetazolamide function experiments have limb deformities, pregnant women should not be used. 10, the treatment of asthma drugs: such as tea thousand, epinephrine, sodium cromoglycate, prednisone, etc. are not teratogenic. 11, anti-convulsant drugs: the incidence of congenital malformations in the fetus of those who take anti-convulsant drugs during pregnancy is 2-3 times higher than the latter. Commonly used are phenytoin sodium, carbamazepine, trimethoprim, valproic acid, etc. 12, antipsychotics have teratogenic effects. 13, sedative drugs: such as Valium, Sulezade, individual teratogenic effect. 14, painkillers: paracetamol can produce liver toxicity. Aspirin can be accompanied by low amniotic fluid, premature closure of the fetal arterial duct. The use of anti-inflammatory pain is contraindicated after 34 weeks of gestation and can cause intraventricular hemorrhage, pulmonary bronchial dysplasia and necrotizing small intestinal colitis in the fetus. 15, antiemetic drugs: no deformity is seen to increase the service tract. 16.Anti-tumor drugs: there are clear teratogenic effects. 17, immunosuppressants: azathioprine, cyclosporine has obvious toxicity to the mother and child. 18, vitamin A: large amounts of use can cause birth defects, the smallest human teratogenic amount of 25000-50000iuld. 19, vitamin A isomers: treatment of skin diseases, isotretinoin embryogenesis with drugs can produce a variety of malformations. 20, etretinate (aromatic retinoic acid): used in the treatment of psoriasis, the half-life is very long, stop > 2 years in the plasma still have drug detection, so at least 2 years before conception. 21, hormones: Danazol, ethylene estradiol, are not suitable for pregnant women, oral contraceptives Shaqiudu subject to a definite teratogenic effect.