1, the cause of adenoid hypertrophy? Repeated upper respiratory tract infections, sinusitis, allergic rhinitis, environmental air pollution, dietary safety and so on. 2, adenoid hypertrophy of the immune base? Adenoid hypertrophy is closely related to type 1 allergic reaction (allergy). Histologic evidence shows eosinophilic infiltration (allergy). Leukotriene receptor overexpression and over-aggregation are present in the adenoids. 3. How can nasal glucocorticosteroids (coxsulam, endocannabinoid, vincristine, etc.) treat adenoid hypertrophy? Decrease eosinophil infiltration Decrease inflammatory mediator release Decrease cytokine production Decrease vascular permeability 4. How do leukotriene receptor antagonists (Shunlin) treat adenoid hypertrophy? Reduces epithelial damage, promotes ciliary oscillation Reduces glandular secretion Reduces eosinophil chemotaxis, aggregation Reduces vascular permeability Reduces cationic protein release Topical glucocorticoid + leukotriene receptor antagonist = dual-pathway anti-inflammatory Combination of drugs is clinically effective and superior to the use of the two drugs alone in the treatment of mild to moderate adenoidal hypertrophy.