Gastric sinus erosion is a gastroscopic finding of a ruptured gastric sinus, which is damaged to the depth of the mucosal layer. However, gastroscopy does not visually reflect the depth of gastric erosion and a gastroscopy is required to clarify it. In addition, if the depth of the erosion exceeds the mucosal layer, it is also clinically known as a gastric ulcer, which is a precancerous lesion. Therefore, when an erosion is found, a biopsy is needed to determine the depth of the erosion and to determine if there is a cancerous lesion. Gastric sinus erosion is directly related to excessive secretion of gastric acid and inattentive eating, such as drinking alcohol. When sinus erosion is detected, it needs to be treated with drugs that inhibit gastric acid and protect the gastric mucosa, clinically with omeprazole or lansoprazole plus rehabilitative new liquid. In addition, the disease is directly related to H. pylori infection. Therefore, when the presence of gastric sinus erosion is detected, it needs to be further clarified whether the bacteria is infected, and if so, it needs to be killed off first.