Clinically, pain is divided into three main categories: injury-receptive pain, neuropathic pain, and psychogenic pain; however, as pain progresses, these types of pain gradually mix together to become intractable pain. Chronic intractable pain, especially neuropathic pain, has long been difficult to treat because of its association with pain syndromes including injury-induced somatosensory disorders, characterized by pain that is specific, unpredictable, and without uniform risk factors. Common clinical disorders, including trigeminal neuralgia, glossopharyngeal neuralgia, postherpetic neuralgia, cancer neuralgia, discogenic neuralgia (disc herniation), diabetic neuralgia, post-stroke neuralgia, post-paraplegic neuralgia, post-amputation stump neuralgia, burning neuralgia, post-peripheral nerve injury neuralgia, and phantom limb pain, seriously affect patients’ quality of life, and some patients even commit suicide because they cannot tolerate this Some patients even commit suicide because they cannot tolerate such severe pain. In fact, there are a number of intractable pains that can be treated, and once treated correctly, the patient’s pain can be relieved immediately. The pain of trigeminal neuralgia was mistaken for toothache, and the treatment was ineffective for many years, but after microvascular decompression, the pain did not occur again. She was afraid to open her mouth to eat, and became cautious of all mouth-related actions. Six months ago, a friend reminded her that she might not have toothache, but trigeminal neuralgia. After the examination, she was diagnosed with trigeminal neuralgia and underwent microvascular decompression, and the pain has not recurred since.