Panic when hearing ear-splitting sound is usually not caused by kidney disease, and is generally considered to be a normal phenomenon, psychological disorders and other factors. 1. Normal phenomenon: ear-piercing sound belongs to a kind of noise, causing the human body to feel uncomfortable, causing panic and irritability and other symptoms is normal, if there are no other adverse symptoms, generally considered to be normal. 2. Psychological disorders: such as depression or anxiety disorders, these diseases can also cause the human body to appear emotionally unstable or easily provoked symptoms, once stimulated by the ear-piercing noise, will induce physical discomfort, causing panic, or even dizziness and cardiac discomfort. 3. Other factors: cardiovascular diseases such as hypertension, coronary heart disease, hyperthyroidism, etc., once you hear the ear-piercing noise, will cause sympathetic nerve excitation, resulting in elevated blood pressure, panic and cardiac discomfort and other symptoms. To summarize, panic when hearing ear-splitting noise is generally not related to kidney disease, if the patient is still feeling panic and discomfort away from the noise, it is recommended to go to the regular hospital as soon as possible to receive checkups and treatments.