Some vaginal inflammatory diseases require anti-inflammatory medication, while others do not. If you have a third degree of cleanliness and there are no other pathogenic infections, you can just douche and plug the vagina without taking oral medication. However, if the infection is Candida, you should take anti-inflammatory drugs such as fluconazole, and if the infection is Trichomonas, you should also take anti-inflammatory drugs such as metronidazole. If the infection is caused by mycoplasma or chlamydia, antibiotics and azithromycin are the first choice for treatment. Therefore, some vaginal inflammatory diseases can be treated with topical medications instead of oral medications. Different pathogenic infections require different clinical treatments. Some of the above mentioned vaginal inflammatory diseases require oral antibiotics.