Application of traditional Chinese medicine in the prevention and treatment of radiotherapy complications

Tumor treatment advocates a combination of therapies. Surgical oncology, medical oncology, and radiation therapy constitute the three major means of malignant tumor treatment. Interventional therapy and targeted therapy are becoming more and more important means. Traditional Chinese medicine is involved in the whole process of tumor treatment. The 5-year survival rate of malignant tumor treatment is improving, from 5% in the early 20th century, 15% in the 1930s, 30% in the 1960s to nearly 45% in the 1990s. …… As the number of cured patients increases year by year, the problem of quality of life after cure is becoming more and more prominent, a successful treatment should be both to cure the patient and to preserve the patient’s quality of life and function. For example, breast-conserving surgery plus radiotherapy for early breast cancer is gradually accepted and recognized. Tumor radiosensitivity depends on their intrinsic sensitivity, tissue origin, degree of differentiation, macroscopic type, tumor bed, anemia, local co-infection, life index, etc. Therefore, anemia should be corrected and infection should be controlled before treatment. Radiosensitive tumors: seminomas, lymphomas, etc. Moderately sensitive tumors: squamous epithelial cell carcinoma, adenocarcinoma, etc. Insensitive tumors: soft tissue sarcoma, osteosarcoma, etc. Radiotherapy with Chinese medicine can prevent and control complications: due to the difference in radiosensitivity of different tumor tissues, normal tissues will be damaged to different degrees. If the vital organs that maintain life activities are damaged, the patient’s life can be jeopardized or seriously disabled; in addition, radiotherapy can also lead to immune function suppression, teratogenicity, carcinogenicity and other dangers in the long term. Radiotherapy kills tumor cells directly and damages normal tissue cells at the same time; while destroying the tumor completely, it avoids and reduces the damage to normal tissues as much as possible, so as to achieve the purpose of curing the tumor, protecting the function, improving the quality of life and prolonging the life. As a traditional medical treatment, Chinese medicine has its advantages in carrying out Chinese medicine to prevent and treat tumor radiotherapy complications. Chinese medicine’s understanding of the etiology of radiotherapy complications: According to Chinese medicine, the etiology of radiotherapy complications is “fire” and “heat toxicity”, which is one of the six evils of wind, cold, summer, dampness, dryness and fire. Heat and toxicity injure yin and deplete qi, damage yin and burn fluids, impair the function of the spleen and stomach, and affect the source of qi and blood biochemistry. At the same time, the body damage caused by radiotherapy may result in blood stasis due to qi deficiency, which should be recognized as warm disease according to the characteristics of the disease. While effectively killing cancer cells, it will cause symptoms of both qi and yin injury. For example, weakness, dry mouth and thirst, dry throat, dry cough with little phlegm, irritability and insomnia, etc. Therefore, radiation belongs to the category of fire and heat poison. Therefore, radiation belongs to the category of fire and heat poison: it fights poison with poison, dispels evil and injures righteousness, and has heat-causing property (aseptic inflammation); it can cause deficiency (bone marrow inhibition, disorder of internal organ regulation); it belongs to the category of warm disease (injury to yin and depletion of qi, disorders of spleen and stomach, and insufficiency of qi and blood). The application of traditional Chinese medicine in the identification of evidence and disease can support the positive qi, reduce the toxic side effects of radiotherapy and maintain the quality of life. It can play the role of potentiation and sensitization to prolong the survival time. Its essence is the holistic concept and the identification of evidence. Diagnosis and treatment: tonifying qi and nourishing blood, strengthening the spleen and nourishing the stomach, generating fluids and moistening dryness, and clearing heat and detoxifying toxins. Disease identification and treatment: low afternoon fever, radiation nephritis, radiation cystitis, radiation proctitis, radiation vaginitis, radiation pelvic inflammation, menopausal manifestations caused by irradiation of the ovaries, tumor lysis syndrome, radiation skin injury, etc.