Rejuvenation is currently one of the hottest topics in the field of cosmetic surgery. Human aging includes the aging, degeneration and atrophy of skin, fat, muscle and bone in all aspects. At present, medical cosmetic surgery mainly focuses on skin, fat and bone rejuvenation, and there are few ways to rejuvenate muscles. The wrinkle removal surgery used for facial skin laxity only lifts the superficial layer of skin and subcutaneous fat, but the deeper atrophied muscles are not improved, and the face often looks flat after surgery, without the fullness of youth. In order to solve this problem, Dr. S. Coleman in the United States filled fat under the skin at the same time as wrinkle reduction to make the face look concave and convex. However, due to the limited survival rate of the filled fat, long-term follow-up found that some of the fat would be absorbed, thus affecting the establishment of a good facial profile. Therefore, fat grafting instead of muscle improvement is not ideal, and the best solution is a direct enhancement of muscle function. So, is it possible to achieve rejuvenation of muscle function? According to my exercise experience during this period of time, after a period of training, the time spent on 5km running can be shortened by 10 minutes (35min→25min). Considering the insignificant difference in the influence of external conditions (e.g. temperature, humidity, etc.), the shortening of the time spent is mainly related to the improvement of internal cardiorespiratory function and muscle function, of which the improvement of muscle function is the most direct manifestation of increasing the speed and shortening the time spent. The improvement of muscle function, including the improvement of muscle cell mitochondrial function and the thickening of muscle fibers, is also the process of muscle tissue rejuvenation. This suggests that muscle function can be improved and muscle rejuvenation can be achieved through exercise of the muscles. For age-related fat accumulation in the trunk extremities after fat aspiration should be combined with regular muscle function exercises to reduce the thickness of the fat layer while restoring muscle vitality to form a healthy and youthful trunk extremity profile and even reveal the vestigial line or mermaid line. In addition, regular muscle contraction can improve muscle function, and in the human body, muscle contraction is produced by the bioelectric effect of nerves. Therefore, is it possible to achieve muscle rejuvenation through in vitro targeted quantitative electrical stimulation acting on the muscles of the face or other parts of the body to restore them to their youthful full form and functional state. In conclusion, I believe that muscle rejuvenation should also be an important part of the aesthetic plastic surgery field and should not be neglected as part of the systemic rejuvenation of the human body. Plastic surgery combined with muscular rejuvenation is expected to achieve a desirable natural youthful contour and a positive mental state.